Often success in business is the result of diligent study of the current marketplace to optimize key differentiating characteristics to grow within an arena in which you are already competitive. But sometimes breakthrough achievement is best pursued through branching out and focusing in a new domain. At the 2018 BioForward Wisconsin BioHealth Summit, Amanda Baltz, Nicolas Paris, and Garrett Peterson got together to discuss new technologies, new markets, and how their organizations pivoted into new business lines: